What is GHK-Cu?
GHK-Cu (Copper Peptide GHK-Cu) is a naturally occurring tripeptide with a high affinity for copper ions. It was first identified in human plasma and declines significantly with age. The peptide-copper complex plays important roles in wound healing, collagen synthesis, and tissue remodeling.
GHK-Cu is one of the most researched peptides for skin health, with studies showing effects on collagen production, antioxidant genes, and tissue repair mechanisms.
The 50mg vial provides extended research duration for daily protocols.
Quick Reference
| Parameter | Value |
|---|---|
| Peptide Amount | 50mg |
| Recommended BAC Water | 2mL |
| Resulting Concentration | 25mg/mL |
| Typical Research Dose | 1-2mg daily |
| Frequency | Once daily |
| Research Duration | 4-12 weeks |
Reconstitution Guide
Step-by-Step Instructions
- Clean vial stoppers — Wipe with alcohol swabs
- Draw 2mL BAC water — Using sterile syringe
- Add to peptide vial — Inject slowly down the wall
- Dissolve — GHK-Cu dissolves quickly, 1-3 minutes
- Label and refrigerate — Store immediately
Note: GHK-Cu solution has a blue tint — this is normal due to the copper content.
Concentration Calculations
With 50mg in 2mL BAC water:
- Concentration: 25mg/mL
- Per unit (U-100): 250mcg per unit
Dosage Protocol
Common Dose Calculations
| Desired Dose | Draw Volume | Syringe Units |
|---|---|---|
| 500mcg | 0.02mL | 2 units |
| 1mg | 0.04mL | 4 units |
| 2mg | 0.08mL | 8 units |
Doses Per Vial
| Daily Dose | Doses | Duration |
|---|---|---|
| 1mg | 50 doses | 50 days |
| 2mg | 25 doses | 25 days |
Suggested Protocols
Protocol A: Standard
- Dose: 1-2mg
- Frequency: Once daily
- Duration: 8-12 weeks
Protocol B: Skin Focus (Topical + SubQ)
- SubQ: 1mg daily
- Plus topical application
- Duration: 4-8 weeks
Injection Guide
Subcutaneous Administration
- Clean site with alcohol
- Pinch skin at abdomen or near target area
- Inject at 45-90° angle
- Rotate sites
Application Notes
GHK-Cu can also be used topically when formulated appropriately, though SubQ provides systemic effects.
Storage Requirements
| Form | Temperature | Duration |
|---|---|---|
| Lyophilized | -20°C | 2+ years |
| Reconstituted | 2-8°C | 4-6 weeks |
Note: Blue color is normal and indicates copper content.
Research Considerations
Mechanism of Action
- Collagen synthesis — Stimulates Types I and III
- Gene expression — Modulates 4,000+ genes
- Antioxidant — Activates antioxidant genes
- Anti-inflammatory — Reduces inflammation markers
- Wound healing — Accelerates tissue repair
Research Areas
- Skin aging and regeneration
- Hair follicle health
- Wound healing
- Collagen production
- Anti-inflammatory effects
Sourcing for Research
Source from verified suppliers that provide third-party testing and certificates of analysis (COA) for each batch. Compare purity documentation, shipping conditions, and batch traceability before purchasing research materials.