What is VIP?
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide found throughout the body, particularly in the gut, brain, and immune system. It acts as a neurotransmitter and has potent anti-inflammatory, immunomodulatory, and vasodilatory properties.
VIP research has expanded into chronic inflammatory conditions, autoimmune diseases, and biotoxin illness protocols. It’s particularly noted in mold illness research.
The 5mg vial provides numerous doses for research protocols.
Quick Reference
| Parameter | Value |
|---|---|
| Peptide Amount | 5mg |
| Recommended BAC Water | 2mL |
| Resulting Concentration | 2.5mg/mL |
| Typical Research Dose | 50-100mcg |
| Frequency | 1-2x daily |
| Research Duration | 4-8 weeks |
Reconstitution Guide
Concentration Calculations
With 5mg in 2mL BAC water:
- Concentration: 2.5mg/mL = 2500mcg/mL
- Per unit (U-100): 25mcg per unit
Dosage Protocol
Common Dose Calculations
| Desired Dose | Draw Volume | Syringe Units |
|---|---|---|
| 50mcg | 0.02mL | 2 units |
| 75mcg | 0.03mL | 3 units |
| 100mcg | 0.04mL | 4 units |
Doses Per Vial
| Dose | Doses | Duration |
|---|---|---|
| 50mcg | 100 doses | 50-100 days |
| 100mcg | 50 doses | 25-50 days |
Suggested Protocol
Standard Protocol:
- Dose: 50-100mcg
- Frequency: Once daily
- Duration: 4-8 weeks
Administration
VIP can be administered:
- Subcutaneous — Standard injection
- Intranasal — Common in some protocols
Storage Requirements
| Form | Temperature | Duration |
|---|---|---|
| Lyophilized | -20°C | 2+ years |
| Reconstituted | 2-8°C | 2-3 weeks |
Important: VIP is sensitive and degrades relatively quickly. Use within 2-3 weeks.
Research Considerations
Mechanism of Action
- Anti-inflammatory — Suppresses pro-inflammatory cytokines
- Immunomodulation — Regulates immune responses
- Vasodilation — Blood vessel relaxation
- Neuroprotection — CNS protective effects
- Circadian regulation — Influences sleep/wake cycles
Research Areas
- Chronic inflammatory conditions
- Mold/biotoxin illness (CIRS)
- Autoimmune research
- Pulmonary hypertension
- Neuroprotection
- GI disorders
VIP in CIRS Protocols
VIP has been studied in Chronic Inflammatory Response Syndrome (CIRS) research, particularly related to mold exposure and biotoxin illness.
Sourcing for Research
Source from verified suppliers that provide third-party testing and certificates of analysis (COA) for each batch. Compare purity documentation, shipping conditions, and batch traceability before purchasing research materials.