What is Tesamorelin?
Tesamorelin is a synthetic GHRH analog with FDA approval (Egrifta®) for HIV-associated lipodystrophy. It stimulates natural growth hormone release with well-documented effects on visceral fat reduction.
The 10mg vial provides 5-10 days of research — better value than the 2mg vial for extended protocols.
Quick Reference
| Parameter | Value |
|---|---|
| Peptide Amount | 10mg |
| Recommended BAC Water | 2mL |
| Resulting Concentration | 5mg/mL |
| Typical Research Dose | 1-2mg |
| Frequency | Once daily |
| Research Duration | 12-26 weeks |
Reconstitution Guide
Concentration Calculations
With 10mg in 2mL BAC water:
- Concentration: 5mg/mL = 5000mcg/mL
- Per unit (U-100): 50mcg per unit
Dosage Protocol
Common Dose Calculations
| Desired Dose | Draw Volume | Syringe Units |
|---|---|---|
| 1mg | 0.20mL | 20 units |
| 1.5mg | 0.30mL | 30 units |
| 2mg | 0.40mL | 40 units |
Doses Per Vial
| Daily Dose | Doses | Duration |
|---|---|---|
| 1mg | 10 doses | 10 days |
| 2mg | 5 doses | 5 days |
Why Choose 10mg
| Factor | 2mg Vial | 10mg Vial |
|---|---|---|
| Doses at 2mg | 1 | 5 |
| Cost per dose | Higher | Lower |
| Reconstitutions | More frequent | Less frequent |
| Best for | Trial | Extended protocols |
Suggested Protocol
Standard (FDA-based):
- Dose: 2mg
- Frequency: Once daily
- Timing: Morning, fasted
- Duration: 12-26 weeks
Storage Requirements
| Form | Temperature | Duration |
|---|---|---|
| Lyophilized | -20°C | 2+ years |
| Reconstituted | 2-8°C | 3-4 weeks |
Research Considerations
Mechanism of Action
- GHRH receptor activation — Pituitary stimulation
- Pulsatile GH release — Natural pattern
- IGF-1 elevation — Secondary effect
- Visceral fat effects — Primary research focus
Clinical Validation
FDA-approved studies demonstrated:
- Significant visceral fat reduction
- Improved trunk fat distribution
- Maintained IGF-1 within normal range
- Well-characterized safety profile
Sourcing for Research
Source from verified suppliers that provide third-party testing and certificates of analysis (COA) for each batch. Compare purity documentation, shipping conditions, and batch traceability before purchasing research materials.