What is Follistatin-344?
Follistatin-344 (FST-344) is the heparin-binding splice variant of follistatin, an antagonist of myostatin and activin. Because myostatin limits muscle growth, follistatin is studied as a myostatin-inhibitor research peptide in muscle-growth contexts. It sits alongside the IGF family in the muscle-repair niche.
Reconstitution
Follistatin-344 reconstitutes with bacteriostatic water. Draw 1mL down the inside wall of the vial, swirl gently until fully dissolved, and refrigerate. Do not shake.
Quick Reference
| Parameter | Value |
|---|---|
| Peptide Amount | 1mg |
| Reconstitution Solvent | Bacteriostatic water |
| Recommended Volume | 1mL |
| Resulting Concentration | 1mg/mL |
| Typical Research Dose | ~100mcg |
| Frequency | daily |
Reconstitution Guide
Materials Needed
- Follistatin-344 1mg lyophilized vial
- Bacteriostatic water (BAC water)
- Insulin syringes (U-100, 29-31 gauge)
- Alcohol swabs
- Sharps container
Step-by-Step Instructions
- Prepare workspace — Clean environment, gather materials, thorough handwashing.
- Clean vial stoppers — Wipe both vials with alcohol swabs. Allow complete drying.
- Draw BAC water — Draw 1mL bacteriostatic water using a sterile syringe.
- Add to peptide — Inject slowly down the inside wall of the vial. Do not spray directly onto the powder.
- Dissolve — Allow a few minutes for complete dissolution. Gentle swirl only — no shaking.
- Verify — Solution should be clear.
- Label and store — Note reconstitution date. Refrigerate immediately.
Dosage Protocol
Concentration Calculations
With 1mg peptide in 1mL BAC water:
- Concentration: 1mg/mL (1000mcg/mL)
- Per unit (U-100 syringe): 10mcg per unit
Run your exact vial and water combination through the peptide reconstitution calculator to rebuild this table for your setup.
Common Dose Calculations
| Desired Dose | Draw Volume | Syringe Units |
|---|---|---|
| 50mcg | 0.05mL | 5 units |
| 100mcg | 0.10mL | 10 units |
| 150mcg | 0.15mL | 15 units |
Research Considerations
Mechanism
By sequestering myostatin and activin, follistatin removes a brake on satellite-cell activation and muscle protein accretion in preclinical models.
Sourcing for Research
Source from verified suppliers that provide third-party testing and certificates of analysis (COA) for each batch. Compare purity documentation, shipping conditions, and batch traceability before purchasing research materials.
Storage Requirements
Lyophilized (Powder)
- Temperature: -20°C or colder
- Duration: 2+ years
- Conditions: Dry, dark, protected from moisture
Reconstituted
- Temperature: 2-8°C (refrigerated)
- Duration: 2-3 weeks
- Conditions: Protected from light, never freeze
Safety Considerations
- Follistatin-344 is a research compound
- Not approved for any indication in any jurisdiction
- Research use only — not for human consumption
- Use sterile technique; never reuse needles or syringes
Scientific References
- Research literature on Follistatin-344 and its proposed mechanism of action.
- Peer-reviewed and preclinical sources on the compound class discussed above.
Last updated: 2026-07-20.
Disclaimer: This information is for educational and research purposes only. Follistatin-344 is a research compound and is not approved for any use. Research-grade peptides are not intended for human consumption. Always follow applicable laws and institutional guidelines.