What is BPC-157?
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide consisting of 15 amino acids. It is derived from a protein found in human gastric juice and has been studied extensively in preclinical research for its potential effects on tissue healing and cytoprotective properties.
Research has examined BPC-157’s effects on various tissues including tendons, ligaments, muscle, and the gastrointestinal tract. The peptide has demonstrated stability in gastric juice and shows promise in multiple research applications.
Quick Reference
| Parameter | Value |
|---|---|
| Peptide Amount | 5mg |
| Recommended BAC Water | 2mL |
| Resulting Concentration | 2.5mg/mL (2500mcg/mL) |
| Typical Research Dose | 250-500mcg |
| Frequency | 1-2x daily |
| Research Duration | 4-12 weeks |
Reconstitution Guide
Materials Needed
- BPC-157 5mg lyophilized vial
- Bacteriostatic water (BAC water)
- Insulin syringes (U-100, 29-31 gauge)
- Alcohol swabs
- Sharps container
Step-by-Step Instructions
-
Prepare your workspace — Clean your work area and gather all materials. Wash hands thoroughly.
-
Clean the vial stoppers — Wipe the BPC-157 vial stopper and BAC water vial with alcohol swabs. Allow to dry.
-
Draw the BAC water — Using a sterile syringe, draw 2mL of bacteriostatic water.
-
Add water to peptide vial — Insert the needle into the BPC-157 vial and slowly inject the BAC water down the inside wall of the vial. Do not spray directly onto the powder.
-
Allow to dissolve — Let the vial sit for 1-2 minutes. Gently swirl if needed — never shake vigorously as this can damage the peptide.
-
Verify dissolution — The solution should be clear. If cloudy or particles remain, continue gentle swirling.
-
Label and store — Write the reconstitution date on the vial. Store properly (see storage section).
Dosage Protocol
Concentration Calculations
With 5mg peptide in 2mL BAC water:
- Concentration: 2.5mg/mL = 2500mcg/mL
- Per unit (U-100 syringe): 25mcg per unit
Common Dose Calculations
| Desired Dose | Draw Volume | Syringe Units |
|---|---|---|
| 250mcg | 0.10mL | 10 units |
| 300mcg | 0.12mL | 12 units |
| 400mcg | 0.16mL | 16 units |
| 500mcg | 0.20mL | 20 units |
Suggested Research Protocol
Weeks 1-2 (Loading)
- Dose: 250mcg
- Frequency: Once daily
- Purpose: Assess tolerance
Weeks 3-8+ (Maintenance)
- Dose: 500mcg
- Frequency: Once daily
- Purpose: Standard research dose
Notes:
- Can be administered once or split into two daily doses
- Subcutaneous injection is the most common route in research
- Rotate injection sites to minimize local irritation
Injection Guide
Subcutaneous Administration
- Clean the injection site with an alcohol swab
- Pinch a fold of skin (abdomen, thigh, or upper arm)
- Insert needle at 45-90° angle
- Inject slowly and steadily
- Wait 5 seconds before withdrawing needle
- Apply light pressure if needed — do not rub
Site Rotation
Rotate between these areas to prevent irritation:
- Abdomen (2+ inches from navel)
- Outer thigh
- Back of upper arm
- Lower back/hip area
Storage Requirements
Lyophilized (Powder Form)
- Temperature: -20°C (-4°F) or colder
- Duration: 2+ years
- Conditions: Protect from light and moisture
Reconstituted (Mixed with BAC Water)
- Temperature: 2-8°C (36-46°F) — standard refrigerator
- Duration: 4-6 weeks
- Conditions: Keep away from light, do not freeze
Important Storage Notes
- Allow vials to reach room temperature before opening to prevent condensation
- Do not freeze reconstituted peptide — causes degradation
- Avoid repeated temperature fluctuations
- Discard if solution becomes cloudy or discolored
Safety & Handling
General Precautions
- Use sterile technique for all preparations
- Never reuse needles or syringes
- Dispose of sharps properly in designated containers
- Store away from children and unauthorized persons
Research Considerations
- BPC-157 is for research purposes only
- Not approved for human use by FDA or other regulatory agencies
- Limited human clinical trial data available
- Consult relevant literature and institutional guidelines
Sourcing for Research
Source from verified suppliers that provide third-party testing and certificates of analysis (COA) for each batch. Compare purity documentation, shipping conditions, and batch traceability before purchasing research materials.
Scientific References
- Sikiric P, et al. “Stable gastric pentadecapeptide BPC 157: Novel therapy…” Curr Pharm Des. 2018.
- Seiwerth S, et al. “BPC 157 and blood vessels.” Curr Pharm Des. 2014.
- Gwyer D, et al. “Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing.” Cell Tissue Res. 2019.
Last updated: December 01, 2024
Disclaimer: This information is for educational and research purposes only. BPC-157 is a research chemical not intended for human consumption. Always follow applicable laws and institutional guidelines.